Expression of Interleukin - 2 Receptor fi Subunit in Hematopoietic Malignancies
نویسندگان
چکیده
The expression of the interleukin-2 (IL-2) receptor was studied in neoplastic cells derived from acute leukemias, T-ceII lymphoblastic lymphomas. peripheral T-ceII lymphomas. chronic lymphocytic leukemias. well-differentiated lymphocytic lymphomas. and established cell lines by both flow cytometric analysis and sodium dodecyl sulfate/ polyacrylamide gel electrophoresis (SDS-PAGE) after affinity crosslinking of radiolabeled IL-2. Cells from most acute leukemias (1 9 of 22), irrespective of their subtype (T. common or nonlymphoid leukemias), as well as T-cell lymphoblastic lymphomas and peripheral T-cell lymphomas expressed only the p70-75 fi subunit of the 11-2 receptor.
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تاریخ انتشار 2005